Sentence examples for modulate toxicity in from inspiring English sources

No general influence of the anionic compound in the ionic liquids on toxicity could be found, although they seem to modulate toxicity in some cases.

However, sequences flanking the polyglutamine tract have profound influences on huntingtin toxicity [33], therefore, our findings are consistent with a process that could modulate huntingtin toxicity in-vivo.

However, changes in expression of Usp15 did not modulate toxicity of a model polyglutamine protein in cell culture.

The UIM domains have been found to modulate toxicity of the pathogenic Ataxin-3 protein (13).

However, at the same concentrations, CQ does not modulate vorinostat toxicity in the parental SUDHL6 cells.

Finally, we used a lentiviral vector (LV) approach (33) to overexpress recombinant Crym in striatal neurons and directly determine whether the protein could modulate mHtt toxicity in vivo in mice.

Our designed compounds modulate r CGG exp toxicity in cellular models of FXTAS, and pull-down experiments confirm that they bind r CGG exp in vivo.

We have also examined the importance of human kinases in modulating Tau toxicity in vivo.

A possible explanation for this might be an interaction with other neurotransmitters in the brain, modulating glutamate toxicity in vivo.

To gain an insight into which of these genes was more likely to be involved in modulating Aβ toxicity in the fly, an Affymetrix cDNA microarray screen was undertaken to search for genes that were up- or down-regulated in flies expressing Arctic Aβ42 as compared to flies expressing the non-toxic Aβ40 peptide [44].

Genomic phenotypic screens have been useful in the past to determine the role of nonessential proteins in modulating toxicity after exposure to an environmental agent [ 1, 5- 10].