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Several studies indicate that transduction mechanisms are intrinsic to cutaneous neurons and that epidermal keratinocytes only modulate this transduction.
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GSH/GGT-dependent pro-oxidant reaction has been found to modulate the transduction of proliferative/apoptotic signals (Accaoui et al, 2000).
The nervous system is a dynamic and plastic structure that modulates the transduction and transmission of neuropathic and nociceptive pain.
The latter's visual toxicities are thought to be due to inhibition of phosphodiesterase type 6 (PDE6), which exists exclusively in the retina and is responsible for modulating the transduction cascade of the photoreceptor response to light.
To facilitate this process, coronaviruses have developed strategies to modulate signal transduction pathways that govern ER function.
Thus, the subcellular localization of RGS14 is distinct from that of RGS12, and this may be reflective of functional differences in the ability to modulate signal transduction, such as the ability of RGS14, but not RGS12, to modulate FGFR-mediated signal transduction.
Other components that potentially modulate signal transduction of TGF-β members derive from the large group of modulator proteins, e.g., noggin, follistatin, and members of the chordin and DAN family.
In the cytoplasm, FKBPs and these drugs modulate signal transduction pathways.
Coupled to hundreds of receptors, G-proteins modulate signal transduction pathways and are important hormonal targets.
Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines.
These findings indicate that green tea and theophylline as well as other chemopreventive agents that modulate signal transduction may have opposite effects on cancers of different histolopathology and cell lineage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com