Sentence examples for modulate this pathway from inspiring English sources

A few ISGs have been reported to modulate this pathway.

In addition, future studies are required to examine the UPRmt pathway in vivo in mammalian models to identify key signaling molecules involved in mitochondrial protective mechanisms, which will further advance our understanding of the diseases associated with mitochondrial dysfunction, and will allow discovery of new targets to modulate this pathway.

Although, studies have demonstrated dysregulation of mTOR signaling associated with pathogenesis, the exact mechanisms by which these various cystoprotein gene products modulate this pathway are not understood.

These data indicate that SERCA2a can target the calcineurin/NFAT pathway and may modulate this pathway through its effect on intracellular Ca2 needed for calcineurin activation [30].

We further show that it is possible to pharmacologically modulate this pathway and restore metabolic equilibrium.

In contrast, lack of IκB kinase-1 did not modulate this pathway.

Nevertheless, further investigation of the effects of modulating this pathway is clearly warranted.

Chemical means of modulating this pathway may be of therapeutic interest in the treatment of AD.

This behavior indicates inhibition of non canonical PCP wnt signaling, and suggests that Prdm5 negatively modulates this pathway.

Finally, the activity of several anti-cancer agents, such as suberoylanilide hydroxamic acid (SAHA) and curcumin, are thought to work in part by modulating this pathway, inhibiting thioredoxin and thioredoxin reductase, respectively [5], [6].

Modulating this pathway might thus represent a potential strategy to reduce the impact of diabetic embryopathies.