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The mammary gland, along with uterine tissue, is a sensitive indicator of the functional activity of the hypothalamic pituitary-gonadal axis so that its histological assessment provides important information about compounds that modulate this activity.
The propensity of pol IV to induce one-base deletion is also well documented, 40) and UmuD and RecA act in concert to modulate this activity.
Its variability does not seem to influence the specificity of GPA2 recognition but is able to modulate this activity by enhancing the defence response.
As GRP78 has a key role in sensing ER stress and subsequent homeostatic responses, agents that interfere or modulate this activity may have therapeutic potential.
The analgesic effects of ketamine result from its ability to modulate this activity through blocks of the NMDA receptor (Fig. 1).
The recent purification of myosin 15 will allow its motility to be tested on different types of cross-linked actin filaments, and to examine how the N-terminal extension might modulate this activity (Bird et al., 2014; Hartman et al., 2011).
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Figures 2A 2C suggest that, at 1 mM glucose, α cells exhibit low KATP-channel activity and that glucose acts by modulating this activity.
We set out to study AR activity within a prostate tumour xenograft model and to examine the role of a potential corepressor protein, PHB, in modulating this activity in a real time in vivo setting.
In such case, a SRI-induced down-regulation of hypothalamic 5HT1A receptors [ 51] may modulate this oxytocinergic over-activity, thereby eventually contributing to an anti-obsessive response.
Additionally, luteolin inhibited PI3K activity in a cell-free system, thereby indicating that luteolin can also modulate the activity of this enzyme via direct interaction with this kinase.
Two nuclear receptors that are expressed in a circadian pattern modulate the activity of this core loop.
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modulate this gene
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