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Manipulation of ethylene biosynthesis or perception allows us to modulate these processes and thereby create plants with more robust and/or desirable traits, giving us a glimpse into the role of ethylene in the plant.
A major research focus has been to understand the cellular and molecular mechanisms that underlie the potentiation of adult neurogenesis and to appreciate how interventions designed to modulate these processes could enhance neural regeneration in the post-ischaemic brain.
These conclusions are further supported by reports of others indicating that cells in the TME influence tumor progression and metastasis through production of growth factors and cytokines that modulate these processes [6], [17].
Arsenicals are able to modulate these processes.
Diet, and particularly dietary lipids, has been shown to modulate these processes [ 7, 8].
Thus, identifying mechanisms that modulate these processes is of crucial priority.
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Regulatory and transcription factors modulating these processes are also valuable in breeding crops with improved nutrient use efficiency and yield performance.
With increased understanding of the different Wnt isoforms mediating proliferation, cell fate specification, and stem cell self-renewal in different cancer types and developmental processes, antibodies targeting different regions of LRP6 may prove to be effective agents for selectively modulating these processes.
Despite VEGFR1 and VEGFR2 can bind VEGFA, VEGFR2 plays the major role in modulating these processes.
Our understanding of the mechanisms responsible for inducing prolonged weakness in intensive care unit patients is limited, and the role of hyperglycemia in modulating these processes is unknown.
In SSc-PAH, ET-1 could stimulate these events on T cells, which become activated, with high LFA-1 and low L-selectin expression, and migrate in the extra-vascular space, while bosentan down-modulates these processes and prevents further priming of circulating naïve T cells.
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