Sentence examples for modulate these behaviors from inspiring English sources

To further understand the role of RHO-1 signaling in adult behaviors it will be necessary to define the upstream activators and downstream effectors that modulate these behaviors.

As shown in Figure 1, the resistance to dopamine-induced paralysis and the BSR of hlh-17 (ns204 ); dop-3 (vs106 ) are not significantly different from the resistance and slowing response phenotypes of dop-3 (vs106 ) and hlh-17 (ns204 ) animals and are consistent with a model in which HLH-17 is functioning in the same genetic pathway as DOP-3 to modulate these behaviors.

However, even with this modest sample size, we can exclude the chance that a single gene of large effect modulates these behaviors.

To further elucidate VSMC response to growth factors and the intracellular signaling cascades that may be linked to ECM-mediated adhesion, we used in vitro assays to study the role of laminin-5 in modulating these behaviors in rat vascular smooth muscle cells (rVSMC).

Specifically, the ERK1/2 form of MAPK mediates signaling by PDGF-AA, PDGF-AB, and PDGF-BB in VSMC, as well as signaling through laminin-5 binding integrins, and is therefore the most likely signaling molecule to modulate these cellular behaviors [ 23- 25].

Because PDGF-BB stimulation increases the overall levels of intracellular MAPK, as well as MAPK phosphorylation, we sought to explore this signaling cascade to determine its role in modulating these rVSMC behaviors on laminin-5 [ 22].

Dabelsteen and Gao [ 5] proposed that the presence of different glycosylation patterns modulate the behavior of these membrane glycoproteins involved in cell signaling.

Surface functionalization of nanoparticles (NPs) is an essential tool to modulate the behavior of these materials both in vitro and in vivo.

Next, we examined whether by introducing decorin, a known antitumoral molecule, to widely used MCF7 (Burdall et al. 2003) human breast adenocarcinoma cells, we could modulate the behavior of these cells.

In addition, by utilizing cultures of MCF7 human breast adenocarcinoma cells and a decorin producing adenoviral vector, we also examined whether targeted decorin delivery can modulate the behavior of these cells.

Our studies have shown that interactions among these molecules and the Hippo pathway modulate the behavior of specific tumors and stromal cells.