Sentence examples for modulate their stability from inspiring English sources

They promote the assembly of tubulin monomers into microtubules and modulate their stability, thus playing a key structural role in the distal portion of axons.

In iron-starved cells, both IRPs are activated for binding to iron responsive elements (IREs) within the untranslated regions of several mRNAs and thereby modulate their stability or translation.

Force can drive conformational changes in proteins, as well as modulate their stability and the affinity of their complexes, allowing a mechanical input to be converted into a biochemical output.

In sharp contrast, we showed here that DNA-PK directly binds and phosphorylates two different p53 mutants, thereby modulating their stability and transcriptional activity.

Importantly, lysine deacetylases do not only control dynamic changes in histone acetylation, but also remove acetyl groups from transcription factors, co-repressor complex subunits and KATs and KDACs themselves thereby potentially modulating their stability and function.

The p Ka of sulfenic acids in proteins could be similarly modulated to regulate their stability and reduce its reactivity toward a thiol.

Dyes are frequently combined with material substrates to modulate their properties, enhance stability, reduce toxicity, and improve delivery.

In addition, lncRNAs can regulate gene expression post-transcriptionally by base-pairing with mRNAs to modulate their translation and/or stability [ 12- 14] and by interfering with RNA-binding proteins to influence splicing and translation [ 14- 16].

Besides the encapsulation of drugs in the inner compartment, the nanoliposome can solubilize hydrophobic drugs, enhance their stability, modulate their blood circulation properties, and hence induce their accumulation to tumor tissues [18].

However, sumoylation does not usually tag proteins to degradation but seems to enhance their stability, modulate their nuclear compartimentalization, sometimes competing with ubiquitin for lysine modifications, with quite a different outcome on cell function [19].

Other mechanisms, like direct interaction with proteins to modulate their activities or increase stability of mRNAs, also occur.