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In general, our study indicates that effects of SNPs on studied cardiometabolic traits could be primary, but due to strong meQTLs in the region, we suggest that these effects are dependent on DNA methylation levels, which further modulate the SNP trait effects.
For instance, personality traits modulate the degree to which amygdala and ventral striatum respond to positive or negatively valenced information (56,57).
The QTLs modulating the GFM trait of these mice were also mapped by Wang et al. (Table 2 of [22]).
Borgy, B. et al. Plant community structure and nitrogen inputs modulate the climate signal on leaf traits.
The present findings provide this evidence by showing for the first time that individual differences in trait anxiety modulate the interplay between emotion-sensitive and executive control brain regions.
A parallel can be made with the fact that quantitative resistance is often controlled by a few large-effect QTLs in association with several minor-effect QTLs which can interact with the major QTLs to modulate the expression of the given trait (reviewed in [ 62]).
Interest in modifier genes keeps growing because of their ability to modulate the expression of monogenic or multigenic traits and diseases [1], [2].
Furthermore, the mating tactics did not modulate the relationships between weapons length and the different post-copulatory traits (Table 3).
We modulate the temperature.
It helps modulate the speed of neurotransmission.
The above curves modulate the Filter 2 cutoff.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com