Sentence examples for modulate the target from inspiring English sources

In order to create a tunable dynamic range, homotropic allostery is employed to modulate the target specific binding.

For the regulation of gene expressions in living cells, the development of new riboswitches allows us to modulate the target gene expression in a tailor-made manner.

Many studies reported that miRNA post-transcriptional editing could alter processing of some miRNAs [ 63] or modulate the target specificity of the mature miRNA [ 64].

Thus, the amount of administered drug should be adequate to yield systemic concentrations that will optimally saturate or modulate the target.

Because of the complexity of transcriptional modulation, this result indicates that reporter insertion in an endogenous gene is more likely to capture molecules that modulate the target in HTS.

The AP2/ERF domain is characterized by approximately 60 70 amino acid residues that constitute a typical helix-turn-helix structure responsible for sequence-specific DNA binding to modulate the target gene expression.

Mobilization of Ca2+ to modulate the targets of its signaling function inside living cells is most easily observed in eggs during their interaction with a fertilizing spermatozoon.

Encapsulation into SSL did not modulate the targeting capacity of M26 35.

For molecularly targeted therapies, measuring tissue concentrations and whether the test drug successfully modulates the target (or a surrogate biomarker predictive of drug action) are important.

An OBD should inhibit the identified target in tumours, but most importantly there should be evidence that modulating the target in tumours consistently leads to growth inhibition.

Our observation of differential regulation of the E spl) complex genes supports the notion that Src modulates the target specificity of Notch.