Sentence examples for modulate the systemic from inspiring English sources

We should not lose sight of this goal as increased knowledge regarding our ability to modulate the systemic immune system also promises novel therapeutic targets and therapeutic agents.

It is important to understand the interactions between cytokines and BM myeloid development so we can better modulate the systemic myeloid environment.

Our data suggest that filtration of particles from injections and infusions by in-line microfilters does not modulate the systemic immune response in the adult critically ill patients and cannot prevent acute lung injury or reduce the duration of mechanical ventilation.

Recent reports show that not only sympathetic mediators, but also the cholinergic pathways modulate the systemic inflammatory response.

A cholinergic anti-inflammatory pathway is known to modulate the systemic inflammatory response to endotoxin.

The site of primary infection plays a key role as it produces inflammatory molecules that modulate the systemic immune response.

Thus, in vivo neutralization of IFN-γ modulated the systemic levels of other cytokines/chemokines as well.

This suggests that IL-28A does not only have a "local" liver-specific role in the antiviral defense but also modulates the systemic antiviral immune response against HCV.

In other studies it was demonstrated that alteration in the gut microflora modulates the systemic cytokine response to hemorrhagic shock, with intestinal bacterial overgrowth of monoassociated E. coli leading to the greatest increase in plasma IL-6 and TNF-α levels [24], [25].

Potential therapeutic and prognostic interventions modulating the systemic inflammatory reaction have to be analyzed in further studies.

The increased mortality may be linked to the concurrent actions of hyperglycemia in modulating the systemic inflammatory process [ 8], increasing the risk of infection [ 8] and exaggerating coagulation [ 9].