Sentence examples for modulate the subcellular from inspiring English sources

Indeed, cell shape and matrix rigidity modulate the subcellular localization of YAP and TAZ and cytoskeletal destabilization and inhibition of cell contractility inactivate YAP and TAZ [168].

The above studies suggest that mDpy-30 and its interacting proteins modulate the subcellular distribution and expression of β1 integrin, as well as cell adhesion/migration.

We propose a model in which the role of oestrogen is to modulate the subcellular localization of SOX9 (Fig. 5).

Next, we examined the effect of the I123L and L146F substitutions on the ability of Nef to modulate the subcellular localization of TCR-CD3.

Thus a family of membrane-bound cAMP-binding proteins has been identified, which modulate the subcellular localization of effector proteins involved in organizing signalling complexes and assuring proper membrane physiology of cardiac myocytes.

All of them contain a transit peptide for targeting the protein to chloroplasts, and they might be localized at the inner envelope membrane as it was previously reported for the pea sequence [ 12], though the FNR-binding domain could modulate the subcellular localization of the protein by the interaction with FNR and/or other proteins.

We examined whether Sema3E/Plexin-D1 signal modulated the subcellular localization of Snail1 in OEC cells.

Since Resveratrol blocked Akt activation it was essential to demonstrate if Akt activation pathway was involved in modulating the subcellular distribution and activation of HSF1, the transcription factor responsible for expression of hsp70 gene.

Many of the changes observed in the present study are also found in human ovarian cancer and therefore validate the use of our model for future mechanistic studies to further define how cytoskeletal organization modulates the subcellular localization of cancer promoting signaling pathways.

In work unrelated to Pin1, Tsai et al proposed a model wherein the phosphorylation state of APP Thr668 would be pivotal in modulating the subcellular distribution of APP and generation of Aβ [4] and/or the amyloidogenic γ-secretase cleavage of APP CTFs [19].

DMOG modulated the subcellular localization of Rac-1 and activation of its downstream target p21-activated kinase (PAK).