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Whether and how these three disordered sequence elements interact with each other, through the peptide backbone and through space, to define or modulate the solution properties of HTT exon1 is a challenging problem that is only beginning to be explored.
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Various amounts of acrylamide (AAm) were added to modulate the lower critical solution temperature (LCST) of the nanocomposites for tailored physiological applications.
The silk fibroin nanofibers with high β-sheet content were added into the silk fibroin solutions to modulate the self-assembly, and to directly induce water-insoluble scaffold formation after lyophilization.
The B4C content is also found to play a key role in galvanic corrosion; its influence is modulated by the solution composition and the materials to which the composite is galvanically coupled.
Therefore, a solution to finely modulate the ONL properties of the composite material is offered by appropriate changes in the composition of the polycarbonate:monomer system.
As chemically bound molecular entities they modulate the functional properties of biomolecules in solution and the surface of supramolecular systems including plasma lipoproteins and cell membranes.
The interaction with numerous molecular partners requires the availability of many different structural solutions to effectively modulate the recognition.
The presence of clay minerals and the strain rate experienced by fault rocks modulate the shifting from cataclasis-dominated towards pressure-solution-dominated deformation.
For example, solutions of isotropic bicelles modulate the amyloid formation of full-length prion protein.
The biochemical recognition will then modulate the PL intensity, displaying a colorimetric change in solution that even can be discerned by naked eyes.
Hypertonic solutions have been demonstrated to modulate the immune system [ 8, 9, 10].
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