Sentence examples for modulate the skeletal from inspiring English sources

PTH therapy is not uniformly effective at all skeletal sites and "life-style" factors may modulate the skeletal response to PTH.

Both in diabetic and in healthy mice, EAA supplements modulate the skeletal muscle redox state by improving the antioxidant defense system as shown by increased superoxide dismutase (SOD) expression and simultaneous decrease in heat shock proteins [ 17].

Taken together, the inability of Dantrolene to modulate the skeletal L-type current in the absence of RyR1 supports the idea that these previously observed effects of Dantrolene on the L-type current [ 19, 25] in normal muscle resulted from altered conformational coupling between RyR1 and CaV1.1.

We designed studies to determine whether the ApoE /– phenotype modulates the local skeletal muscle and systemic inflammatory (plasma) responses to lower extremity demand ischemia.

While this subunit is clearly non-essential for activation of the L-type Ca2+ channel and for triggering skeletal-type EC coupling, γ1 appears to specifically modulate the Ca2+ channel function of the skeletal DHPR.

Along with MRF genes, we observed the up-regulation of Tsh3, ARX, meis1 and the homeodomain containing protein pbx1, all of which have been reported to modulate the activity of MRF during skeletal muscle differentiation [ 19- 22].

These results suggest that a minimal number of dmCpG sites or select sites are required to be altered in order to inversely modulate the gene expression in aging skeletal muscle.

Conversely, the skeletal muscle of sedentary older adults fails to modulate the intracellular environment which is thus prone to ROS-mediated toxicity and aberrant redox homeostasis.

The glucocorticoid-driven GR-KLF15-BCAT2 axis may negatively modulate the intracellular availability of BCAAs resulting in a negative impact on mTORC1 function in skeletal muscle.

We modulate the temperature.

It helps modulate the speed of neurotransmission.