Sentence examples for modulate the protective from inspiring English sources

Furthermore, polymorphisms in the toll-like receptor 2 gene (TLR2; GenBank accession no. U88878; http://www.ncbi.nlm.gov) appear to modulate the protective effect of the farm environment: only carriers of certain TLR2 polymorphisms are protected by this environment (Eder et al. 2004).

Founded in 2016 by Cathryn R. Nagler, PhD and Jeffrey A. Hubbell, PhD, ColstraBio is making strides in the discovery and development of new therapeutics that modulate the protective ability of the microbiome.

The capacity of PEA to modulate the protective responses during inflammation suggests that endogenous PEA may be part of the complex homeostatic apparatus controlling the basal threshold of inflammatory processes.

Therefore, in the current study, we aimed to answer three research questions: 1) does T1DM affect the tolerance for IR?; 2) does T1DM modulate the protective effect of ischemic preconditioning?; and 3) is the effect of T1DM on these parameters dependent on the plasma glucose and insulin concentrations?

It is possible that in parasitic infections, where the parasites down modulate the protective immune response, the presence of sCD40L is important to restore this response.

Since sex hormones have been shown to modulate the response to T/HS and proestrous (PE) females are more resistant to T/HS-induced gut and distant organ injury, the goal of our study was to determine the contribution of estrogen receptor (ER)α and ERβ in modulating the protective response of female rats to T/HS-induced gut and lung injury.

Consequently, it is suggested that Rho-kinase acts as a negative regulator of PI3K activation, and modulates the protective effect via PI3K/Akt/eNOS pathway on myocardial PreC and PostC.

sig2, in contrast, appears to play a more minor role in heat shock protection and may serve to modulate the expression of some heat protective genes.

We also show that there is no major dysfunction in the balance of pro- and anti-inflammatory interleukins that modulate the production of toxic and protective kynurenine-related metabolites of tryptophan.

Lastly, exploring features of the home environment and, specifically, characteristics of mother-infant interactions and the child-rearing practices of other caregivers would have added useful information on risk and protective factors that might modulate the effect of maternal CMD exposure upon infant development.

Our sample size was sufficiently large to allow conclusions to be drawn regarding the comparison with normative data, but a larger sample size is needed for examining with sufficient power the possible roles of gender, type of short stature, and risks and protective factors that may modulate the psychosocial functioning of these adolescents [ 42].