Sentence examples for modulate the pathway from inspiring English sources

First, PIM1 is a phosphokinase and phosphorylation of components in the RLR pathways is a common mechanism to modulate the pathway (Bachmann and Moroy, 2005; Quicke et al., 2017; Ivashkiv and Donlin, 2014).

It is likely that cucurbitacin I acts upstream of JAK2 and STAT3 by inhibiting some as-yet undefined component of this pathway or that the compound indirectly affects the pathway by inhibiting some factor that may feed into or modulate the pathway.

Moreover, these effects arise after lifelong exposure, suggesting that limited short-term use of agents that modulate the pathway could be safe and suitable for clinical practice.

Overall, additional elements can modulate the pathway structures in highly non-trivial ways, and this provides some insight into how additional elements in cellular signalling systems may act to modulate and control signal splitting between pathways.

A proper characterization of a pathway's structure is important for identifying the optimal protein to target as well as what concentration of the targeted therapy is required to modulate the pathway in a safe and effective manner.

A proper and detailed characterization of a pathway's structure is important for identifying the optimal protein to target as well as what concentration of the targeted therapy is required to modulate the pathway in a safe and effective manner.

A 'core' protein is essential for transmitting the signal of its pathway, while a 'non-core' protein modulates the pathway's core proteins but not transmit the incoming signal.

These investigations exploited conserved regenerative models (blood and liver) and a chemical screening approach, combined with the vast array of established tools for modulating the pathways of interest.

Oon, S., Wilson, N. J. & Wicks, I. Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathway.

Hsueh and his colleagues then wondered what would happen if ovaries activated through fragmentation were also treated with a substance to modulate the PTEN pathway they inhibited in their 2010 work.

It seems that the autologous bone marrow derived MSCs transplantation may be a promising procedure in order to modulate the degenerative pathway and restore the osteochondral defects.