Sentence examples for modulate the normal from inspiring English sources

Therefore, changes in expression of the tau gene, alternative splicing of its mRNA and its posttranslational modification can modulate the normal architecture and functions of neurons as well as in a situation of tauopathies, such as Alzheimer's disease.

In lieu of direct actions on inflammatory cells, SCAR2B appears to modulate the normal maturation of phagosomes and autophagosomes [ 44, 45].

The relative bioavailability of these nutrients could modulate the normal stochastic changes in methylation that occur due to aging and may be reflected in tumor DNA methylation.

In this paper, we propose control laws for friction dampers which maximize energy dissipation in an instantaneous sense by modulating the normal force at the friction interface.

The understanding of viral mechanisms modulating the normal cellular processes will be a key to the design of an effective control strategy for PRRS.

To obtain the machining parameters for ripple formation, feeds from 20 nm to 50 nm at 10-nm increments were investigated under different scratching angles by modulating the normal load.

Collectively, these findings suggested that cadmium impaired the reproductive process and spermatogenesisand also potentially modulated the normal hormone levels during the toxic response to cadmium in testis.

The rationale of using AS in chemical burns derives from the fact that it contains antiproteases such as alpha 2 macroglobulin (which reduces collagenase) and vitamin A (which modulates the normal growth and differentiation of the epithelium) [ 38, 67].

Our findings point to the importance of using therapeutic strategies directed at modulating the normal compensatory mechanism seen after CNS insult so that its harmful effects can be minimized.

Our ability to modulate alternative splicing within exon 11 ASOs raises an extremely intriguing possibility for future studies that it might be possible to use ASOs to modulate the physiologically normal alternative splicing event that occurs within exon 10.

Many questions remain unanswered, but the results have begun to suggest ways in which emotional structures in the brain might modulate the function of normal sensory and motor neural circuits.