Sentence examples for modulate the network from inspiring English sources

If the PAX1 gene acts to modulate the network, it is therefore likely to affect more than one network member.

While the first approach can alter the underlying network structure permanently, the second one uses external control to modulate the network dynamics.

By quantifying the druggability of particular genes in a disease-associated network, DrugFEATURE can be used systematically to estimate the potential of drug and drug-like molecules to modulate the network.

Granulocytic differentiation of 32Dcl3 is induced by G-CSF and is suppressed by IL-3, suggesting that Xbp1S may modulate the network of cytokine signaling by switching downstream transcriptional regulation in differentiation processes.

It is also possible that other systems involved in maintaining protein homeostasis modulate the network by regulating synthesis and degradation of some of these chaperones.

It selectively suppresses helper T-cell function and modulates the network of inflammatory cytokines.

Cyclic adenosine monophosphate (cAMP), a naturally occurring secondary messenger, helps maintain homeostasis by modulating the network of pro-inflammatory and anti-inflammatory mediators [ 53]. cAMP levels are regulated by phosphodiesterases (PDEs), intracellular enzymes that convert cAMP to AMP [ 53].

A number of therapeutics have been developed or are under development aiming to modulate the coagulation network to treat various diseases.

Apart from their haemodynamic effects, circulating catecholamines themselves can modulate the cytokine network and thereby regulate both suppressive and stimulatory effects on immune responses.

IVIg can inhibit complement activation and infiltration of leukocytes, modulate the cytokine network and inhibit neuronal apoptosis by cleaved caspase-3 in mouse models of ischemic stroke.

Understanding how chronic periodontitis can modulate the cytokine network driving arthritic immune responses before clinical bone destruction takes place is therefore of great interest in relation to developing preventive periodontal therapies in susceptible populations.