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Probiotics have the potential to healthfully modulate the gut microbiome.
Therefore, the aim of this study was to modulate the gut microbiota by antibiotic therapy to investigate effects on parameters reflecting cholesterol metabolism and oxyphytosterol concentrations.
Pharmacomicrobiomics thus may have at least two global clinical applications: 1) to combine personal microbiome and genetic profiles to better predict an individual's medication response; and 2) to modulate the gut microbiome to improve drug efficacy on the individual level.
A multitude of studies supports the use of HMs, herbal formulas, and phytochemicals, such as Gegen Qinlian Decoction formula (Xu et al. 2015), Qushi Huayu Decotion formula (Yang et al. 2017), Rhizoma coptidis (Xie et al. 2011), and quercetin (Li et al. 2016), to modulate the gut microbiota.
In contrast, RS significantly affected several groups of colonic bacteria, with the two types of RS exerting functional differences in terms of their ability to modulate the gut microbiota.
Given that prebiotics target multiple metabolic impairments associated with NAFLD, investigating their ability to modulate the gut microbiota and hepatic health in patients with NAFLD is warranted.
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Other properties may also contribute to carmint's mechanism of action, however, since both peppermint and lemon balm essential oils and extracts have been shown to have antispasmodic activity [ 57, 58], peppermint has also been shown to act on serotonin receptors [ 121] and lemon balm reduces stress [ 122] and could therefore modulate the gut-brain axis.
Therefore, the addition of Astragalus to feed may be beneficial for modulating the gut microbiota of young hens.
Engineering commensal organisms for challenging applications, such as modulating the gut ecosystem, is hampered by the lack of genetic parts.
Supplementation with the herbal extract YGD reduced energy and macronutrient intake by modulating the gut hormones in overweight and obese women.
Meanwhile, CM and PR significantly modulated the gut microbiota of the high-fat diet (HFD) treated mice, similar to metformin, and CM-PR reversed the overall microbiota composition similar to the normal chow diet (NCD) treated mice.
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