Sentence examples for modulate the fate from inspiring English sources

Further, alterations in pyrophosphate binding are thought to aid in the modulation of prenyl chain orientation within the active site and most likely modulate the fate of the early intermediates along prescribed mechanistic pathways 30).

In order to modulate the fate of transplanted cells, we advocate transplanting gene-modified neural precursor cells.

The design of biomimetic scaffolds suitable for cell-based therapies is a fundamental step for the regeneration of the damaged nervous system; indeed growing interest is focusing on the discovery of peptide sequences to modulate the fate of transplanted cells and, in particular, the differentiation outcome of multipotent neural stem cells.

We recently reported that neurotrophic factors, including NGF, modulate the fate of hES cells and promote the differentiation into BFCNs [12].

RT1-C/E/M incompatibility has been shown to induce skin and pancreas graft rejection [26] and to modulate the fate of MHC class II-mismatched heart grafts [27].

Haptoglobin (Hp) is a protein whose primary function is to modulate the fate and toxicity of extracorpuscular hemoglobin [ 7].

Notably, these findings highlight the potential of using surrogate nano-stromal niches to modulate the fate-determination pathways of precursor cells towards a desired phenotype.

Besides the direct effect of the virus on the development of NSPCs, here we wanted to investigate how JEV-induced inflammation modulates the fate of these cells, and whether the use of the anti-inflammatory compound minocycline reverses these effects.

Together these results raised the intriguing hypothesis that inflammation can induce an increase in the ubiquitin pathway that also modulates the fate of PARs [ 76].

Moreover, we demonstrated that Parachlamydia may survive to human macrophages [ 12], by remaining somehow unrecognized from these major innate immune cells [ 13], by modulating the fate of the Parachlamydia-containing vacuole [ 14], and by inducing macrophage apoptosis [ 12].

The delay of the loss of the pistil responsiveness to GAs by blocking the ethylene response, using both genetic mutants (ein2-5 and ein3-1) and pharmacological treatments (1-MCP and STS), further support the role of ethylene in modulating the fate of the unfertilised pistils in Arabidopsis.