Sentence examples for modulate the differentiation from inspiring English sources

In addition, Wnt and Notch pathways have been known to modulate the differentiation of hepatocytes or billilary epithelial cells17.

The present study investigated the ability of two polymers (pHM1 and pHM3) with different positive surface charge densities to modulate the differentiation of MSCs into osteoblast-like phenotype via cell-cell ephrinB2/EphB4 signaling.

Quiescent HSCs or culture-activated HSCs do not have the ability to modulate the differentiation of MSCs.

In this study, we hypothesize that corneal wounding may modulate the differentiation of corneal epithelial cells due to a disrupted BM, resulting in de-differentiation of corneal epithelial cells, i.e., the likely progenitor cells of corneal epithelium.

Cytokines secreted by B cells can modulate the differentiation and functions of several key immune effectors, such as CD4 and CD8 T cells, NK cells and dendritic cells [5].

Retinoids modulate the differentiation and functions of both lymphocytes and DCs.

However, whether PCA modulates the differentiation of NS/PCs has remained to be elucidated.

The influence of the GHA matrix on cell growth and on modulating the differentiation ability of mesenchymal stem cells was evaluated by different biochemical and immunostaining assays.

Although the frequency of Pro-E, Ery-A, and Ery-B was greater in P38α−/− BM compared to P38α+/− BM, the frequency of Ery-A, Ery-B, and Ery-C within the Ter119+ population was comparable between P38α+/− and P38α−/− mice, suggesting P38α may not be involved in modulating the differentiation of these subsets during stress erythropoiesis (Fig. 1i).

In order to explore mechanisms putatively involved in the observed changes, the content of different inflammatory cytokines (IL-6, IL-10, IFNγ), myeloid chemoattractant chemokines (CCL-2, CCL5, CXCL1), and growth factors modulating the differentiation of myeloid cells (G-CSF, GM-CSF) or vessel growth (VEGF), was measured in the peritoneal lavage (Fig. 2).

In summary, this study proved for the first time the potentials of baculovirus in modulating the differentiation status of chondrocytes in the context of cartilage tissue engineering, but also highlighted the importance of selecting appropriate cell passage and growth factor for genetic manipulation.