Sentence examples for modulate the catalytic from inspiring English sources
By contrast, in the incubation containing only CYP2C9, diclofenac hydroxylation was activated by the presence of CYP2C19, thus demonstrating that CYP CYP interactions can modulate the catalytic rates of a variety of oxidation reactions but that this modulation is highly dependent on the substrate undergoing metabolism, with some substrates activating metabolism and others inhibiting it.
Doping is an important approach to modulate the catalytic properties, for example, the change of the overpotential, of TiO2 semiconductor for water splitting.
Metabolic flux is in part regulated by endogenous small molecules that modulate the catalytic activity of an enzyme, e.g., allosteric inhibition.
Precisely, an oxidizing feed was shown to stabilize the Wells Dawson compound, i.e. delay the irreversible transformation of the structure to a mixture of oxides, and thus may be used to modulate the catalytic behavior of the catalyst.
Here, we explore the potential of computational protein design to predict mutants of the imipenemase IMP-1 that modulate the catalytic efficiency of the enzyme against a range of substrates.
If present at DNA gaps, these proteins would bind to the exposed ssDNA or dsDNA in the vicinity of the gap and could modulate the catalytic function of WRN.
This type of binding may induce a conformational change in the acyl pocket loop which modulates the catalytic site via a domino effect.
These results suggest that the role of the N-terminal domain is rather that of targeting the protein in the cell, probably to glycogen and the protein complexes attached to it, rather than that of directly modulating the catalytic activity.
The purpose of this study was to determine if association of MMP-2 with the plasma membrane also modulates the catalytic efficiency of the active enzyme.
It thus appears that the NEIL1 G83D mutation modulates the catalytic capacity of NEIL1 as well as substrate specificity.
Here we present the discovery of a new form of SULT1A1 allosteric regulation that modulates the catalytic efficiency of the enzyme over a 130-fold dynamic range.
