Sentence examples for modulate the apoptotic from inspiring English sources

Among the oncogenes, which may modulate the apoptotic process, Kit/Stem Cell Factor has a peculiar interest, since Kit is expressed in germ cells to some extent and Leydig cells, whereas SCF is expressed in Sertoli cells.

The PKC δ and η also modulate the apoptotic response of keratinocytes exposed to UVB [36], [37].

We then investigated the potential mechanism by which cyclin D1 might modulate the apoptotic response.

Recent studies have shown that STATs can modulate the apoptotic programme in a variety of cell types [5].

Substantial data support a role for mTOR signalling through the eIF4E pathway in promoting cell survival, although exogenous factors may modulate the apoptotic response to mTOR inhibition.

Another study suggested that melatonin may modulate the apoptotic process in the small intestine of mice exposed to 2.5 Gy gamma irradiation [ 60].

The study of mRNA profile of the transfected cells indicated that all Vpr proteins modulated the apoptotic genes triggering the intrinsic pathway of apoptosis.

Both triterpenes successfully modulated the apoptotic response, promoting nuclear condensation and fragmentation.

Based on this initial report, the aim of the present study was to further characterise the pathways modulating the apoptotic process in activated human HSCs.

Future work will need to be done to clarify the mechanistic role of the hypoxia/HIF-1 pathway in modulating the apoptotic response of NPCs after irradiation.

Moreover, this miRNA can indirectly regulate the levels of the oncogene MCL1, further modulating the apoptotic potential of CLL cancer cells by controlling cellular survival [ 104].