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To evaluate, in a new original in vitro assay, putative factors that could modulate the adhesion of endometrial cells to peritoneum.
We therefore asked whether PAPC could modulate the adhesion disrupting activity of FLRT3.
With the intention to drastically modulate the adhesion extent, we used two different postoperative immobilization protocols.
As they can bind to extracellular glycoconjugates, galectins might modulate the adhesion between adjacent cancer cells or between cancer cells and ECM.
Other cytokines such as tumor-necrosis factor- α (TNF- α) in the BM can modulate the adhesion of MM cells in the BM by inducing nuclear factor- (NF-) κB.
This multifunctional protein is also known to be involved in endoplasmic reticulum (ER) associated pathways but when expressed on the cell surface it can modulate the adhesion properties where it has been reported to complex with integrins [ 70, 71].
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We demonstrate that Notch pathway modulates the adhesion of BM-PC to extracellular matrix (ECM) in vitro via regulation of integrin alpha3beta1; and that Notch pathway inhibition on BM-PC impairs their capacity to stimulate endothelial cell tube formation on matrigel and to promote endothelial monolayer recovery following wounding in vitro.
DHEA modulated the adhesion molecule expression in endothelial cells and neutrophiles, and most effects were detectable within the physiological concentration.
Recently, it was shown that miR-124 directly regulates the stability and translation of integrin β1 mRNA in order to modulate the intercellular adhesion of the leading cells in tumors during collective invasion [ 28].
These effects may result from the failure to activate integrin β1-dependent signals that modulate the remodelling of adhesion complexes.
The latter are well known to modulate the expression of adhesion molecules during the metastatic process [ 17, 18].
More suggestions(15)
influence the adhesion
modulate the risk
modulate the wavelength
modulate the volume
modulate the bone
modulate the effectiveness
modulate the speed
modulate the degree
modulate the cation
modulate the light
modulate the effect
modulate the invasion-metastasis
modulate the histone
modulate the host
modulate the response
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