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PV system is by nature a controlled current source, where different electrical control strategies are incorporated to modulate the active and reactive current outputs.
The soma to germ transformation in these mutants is antagonized by the ISW-1 complex and the MES-4 complex (Cui et al., 2006; Stielow et al., 2008), which appear to modulate the active chromatin structures.
However, further studies are required to examine how these mutations modulate the active conformation of vinculin in FAs.
This report accordingly highlights the potential role of RNA helicases, RNA chaperones, or RNA annealers that are expected to either directly affect the sequential enzymatic action of NS5B and/or to modulate the active structure of the RNA template.
In Cg10062, His-69 is replaced with an isoleucine, which could affect this interaction and perhaps alter the position of His-28 and/or otherwise modulate the active site properties.
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NZ modulated the active region structure and completed the MBE growth.
These findings showed that cytochalasin B inhibited glucose uptake and transport by modulating the active binding sites of GLUTs and not by degrading the actual GLUTs protein contents.
It is known that pathogenic mutations near the C-terminus of the Aβ sequence in APP can lead to increased generation of Aβ42 by modulating the active sites of γ-secretase.
The distinction between residues that are directly involved in catalysis through, for instance, nucleophilic attack or proton transfer (such as D105 and H300) and those that act by electrostatically modulating the active site is proving to be subtle.
In summary, the above experimental results suggest that the pZBD in GluRS not only affects the local interaction with tRNAGlu acceptor arm (thus modulating the active site) but also affects the catalytic step of glutamylation reaction indicating some distant communication with other part of the protein.
These methylation marks collectively modulate the transcriptionally active or repressive states of the chromatin complex.
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influence the active
modulate the electronic
modulate the ionospheric
modulate the endogenous
modulate the functional
modulate the atmospheric
modulate the asexual
modulate the swCNT
modulate the visible
modulate the reprogramming
modulate the folding
modulate the inflammatory
modulate the symbols nonregenerative
modulate the cortisol
modulate the biological
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