Sentence examples for modulate the accumulation from inspiring English sources

In eucaryotes, antibiotic efflux pumps modulate the accumulation of antimicrobials in phagocytic cells and play major roles in their transepithelial transport.

Pgp (ABCb1) and Mrp1 (ABCc1), highly expressed in the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB) respectively, may modulate the accumulation of UCB in brain.

However, this is the first time that pH is shown to modulate the accumulation and extrusion of an efflux pump substrate such as EB.

However, the co-culture of stromal cells from Tlr4−/− mice with epithelial cells from WT mice, or vice versa, provided little evidence of interaction between the stromal and epithelial cells to modulate the accumulation of inflammatory mediators except for PGE, which may reflect the endocrine roles that PGE has in reproductive biology [30].

Its counterpart in barley is thought to modulate the accumulation of storage products during grain-filling [ 48].

3- (or 7-) oxidation has potential to modulate the accumulation of cholesteryl esters in foam cells, although this remains to be demonstrated formally.

We therefore sought to test whether oxidants or antioxidants might also impact galactose sensitivity by modulating the accumulation of gal-1P in our GALT-null Drosophila.

H6 also modulates the accumulation of peptide deposits in the brain, with H6/14A showing remarkably high levels of Aβ deposition, higher than H14A alone.

It will be important to determine the functional and temporal relationships among these established modifications in modulating the accumulation of PHF-tau in AD and other age-related neurodegenerative diseases.

Here, we show that a subset of DNA damage checkpoint proteins, Mec1, Rad17, Rad24, Rad9 and Rad53, has a crucial function in Exo1 phosphorylation and consequently modulates the accumulation of ssDNA at uncapped telomeres (this paper and Jia et al, 2004).

How do environmental and genetic factors modulate the rate of accumulation of age-associated damage?