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Diogenes, M. J. et al. Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.
Thus, dopaminergic afferents to the NAc may modulate synaptic transmission either by releasing dopamine (DA) directly onto synapses or by causing a more diffuse increase in extracellular DA levels (Garris et al, 1994; Grace, 1991; Descarries et al, 1996).
However, wider application of this methodological approach to more differentiated cells such as neurons would also be useful for the screening of compounds that modulate synaptic transmission.
IL-1β can powerfully modulate synaptic transmission in the spinal cord by enhancing excitatory synaptic transmission and suppressing inhibitory synaptic transmission.
We have also demonstrated that proinflammatory cytokines and chemokines (e.g., TNF-a, IL-1b, and MCP-1) can powerfully modulate synaptic transmission in the spinal cord, by enhancing excitatory synaptic transmission and suppressing inhibitory synaptic transmission.
ASIC1 is the most abundant of all the ASICs and is likely to modulate synaptic transmission.
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Perea, G. & Araque, A. GLIA modulates synaptic transmission.
Brain-derived neurotrophic factor (BDNF) modulates synaptic transmission in frontostriatal circuits, and these circuits are critical for executive functions.
Metabotropic glutamate receptors (mGluRs; mGluR1-8) arexpresseded throughout the CNS and are important for modulating synaptic transmission and plasticity.
Microglia also play critical roles in shaping neuronal networks during development, and in the adult animal by modulating synaptic transmission [21,23].
Phosducin is an abundant photoreceptor protein that binds G-protein βγ subunits and plays a role in modulating synaptic transmission at photoreceptor synapses under both dark-adapted and light-adapted conditions in vivo.
More suggestions(15)
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