Sentence examples for modulate specifically from inspiring English sources

Recent findings propose that some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) have the ability to modulate specifically γ-secretase activity without inhibiting the enzyme as a whole.

We here made use of an immunocytokine to modulate specifically and locally the immune response.

Of note, these genetic manipulations did not alter food intake, indicating that estrogens actions in the VMH modulate specifically energy expenditure.

In other words, while both J16 cells and HJ16 cells will manifest similar iron uptake by TfR1, the gradual adaptation of cells to H2O2 modulates specifically the FtH subunit of Ft. This modulation does not affect the overall labile iron levels in cells consistent with the notion that iron homeostasis in HJ16 cells is still effective in maintaining a low basal level of intracellular LIP.

However, the mechanism of noncanonical translation initiation via "ribosomal shunt" enables us to design translation initiation-modulating (specifically, ribosomal shunt-modulating) eukaryotic ON riboswitches.

It was recently shown that only the apamin-insensitive portion of the post-burst AHP is reduced after olfactory-discrimination learning [13], suggesting that learning modulates specifically the sIAHP.

A detailed investigation of the digital expression data revealed that 7110 and 6729 genes were modulated specifically by drought and high temperature stress, respectively.

Transcripts modulated specifically in amastigotes showed generally a higher accumulation than promastigote-upregulated transcripts, with 31% of the transcripts demonstrating more than 3-fold increase in expression levels (average of 9.5-fold) (Table 1).

Conjugated to monovalent or multivalent IgG fragments, these peptides could generate new antibody formats for the therapeutic treatment of tumors or infection, in addition to modulating specifically the activation-inhibition balance mediated by FcγRs (46, 47).

An orthotopic biliary tract cancer model in which AGR2 expression can be modulated specifically in the biliary tract might be required to provide more definitive evidences on in vivo tumor-promoting function of AGR2 in biliary tract cancers.

Taken together, these observations have led some commentators to conclude that activation in TPJ and MPFC may be modulated specifically by differences among particular types of mental content to be inferred (e.g., Van Overwalle 2009).