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These BMDCs have been shown to modulate resistance to VEGF blockade in these tumor models [25].
Substitutions at 253 are known to modulate NA antigenicity [15] and substitutions at residue 274 are known to modulate resistance to oseltamivir [16], [17], [18].
Assuming that the studied SNPs have an effect on the functioning of the innate immune system, different SNPs may also be working at different time points to modulate resistance to IA and eventually constitute the hosts genetic signature of susceptibility.
YPT6 codes for a RAS-like GTPase required for fusion of endosome-derived vesicles with the late Golgi and is homologous to the C. elegans LAG rab-10 [13], which is thought to act in the same pathway as dietary restriction (DR) and has recently been shown to modulate resistance to polyglutamine toxicity in a nematode model of Huntington's disease [18], [19].
Glycosylation processes are under high natural selection pressure, presumably because these can modulate resistance to infection.
In this study, we set out to investigate the mechanism by which different antidepressants modulate resistance to oxidative stress.
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Sorbitol modulates resistance to Alternaria alternata by regulating the expression of an NLR resistance gene in apple.
Jud, A. N., Iglesias, A., Wilf, P., and Gandolfo, M. A. American Journal of Botany 0. Sorbitol Modulates Resistance to Alternaria alternata by Regulating the Expression of an NLR Resistance Gene in apple.
We conclude that the miR-193b modulates resistance to doxorubicin in human breast cancer cells by downregulating MCL-1.
The trend of up-regulated RTK activity that modulates resistance to EGFR-targeted therapies is also observed with HER2.
Involvement of the mdr1 gene in chloroquine resistance has been challenged, but variation at codon 86 of this gene modulates resistance to chloroquine (10 ).
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