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This paper shows excellent use of genetic tools to modulate regulators of developmental gliogenesis during glioma tumorigenesis to affect glioma subtype identity.
Paricalcitol and alfacalcidol modulate regulators of vascular calcification.
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Results suggested that the TNFα/nSMase/ceramide pathway modulates key regulators of both myeloid differentiation and erythropoiesis.
It modulates key regulators of melanocytes through transcriptional activation or repression.
But, they subvert and control the polymerization of actin filaments by modulating cellular regulators of this process [ 5].
Nrf2 is thought to have its proangiogenic effects by modulating known regulators of angiogenesis, such as VEGF, in response to oxidative stress [ 116].
Paracrine HGF/Met signaling can control the survival and proliferation of luminal progenitors and affects their fate by modulating antagonistic regulators of basal- (p63, Snail2) and luminal-specific (Elf5, Hey1) regulators.
Except for ETEC, which produce the heat-labile (LT) and heat-stable (ST) enterotoxins that are their main virulence factors [ 36], the other five pathotypes subvert and control the polymerization of actin filaments by modulating cellular regulators of this process.
ARTD8 protects B-cells from apoptosis by modulating key regulators of apoptosis, such as caspase-3 [ 31] and is also necessary for pro-survival signaling and regulation of glycolytic rate in B-cells [ 32].
The lifetime of Gα·GTP is modulated by RGS (regulators of G-protein signaling) domain-containing proteins [4].
GABABR-GIRK signaling is negatively modulated by the Regulators of G protein Signaling (RGS) proteins, which accelerate G protein inactivation (Hollinger and Hepler, 2002; Padgett and Slesinger, 2010).
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CEO of Professional Science Editing for Scientists @ prosciediting.com