Sentence examples for modulate protein aggregation from inspiring English sources

Burke, K. A., Yates, E. A. & Legleiter, J. Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.

In vivo aggregation was computed using AGGRESCAN, an algorithm based on an amino acid aggregation-propensity scale derived from in vivo experiments and on the assumption that short and specific sequence stretches modulate protein aggregation.

GSK3 activity can thus modulate protein aggregation induced by puromycin.

(2) In addition to genes that influence protein folding, multiple genetic loci that participate in gene expression homeostasis, such as RNA-binding proteins, should modulate protein aggregation in vivo.

In conclusion, phosphorylation of NBR1 by GSK3 on Thr586 modulates protein aggregation induced either by a drug or by a pathological mutant protein.

The overall analysis suggests that natural selection modulates proteins aggregation propensities according to their cellular function, structure, concentration and localization.

Thus, it may be that H2S protects the proteostasis network against hypoxia-induced protein aggregation by modulating the ubiquitin proteasome system.

Protein aggregation induced by modulating conditions in solution (e.g. thermal stress and agitation) was monitored over discrete time periods.

It has been suggested that evolution exploits negative design principles to modulate protein deposition by placing residues that counteract aggregation at the flanks of hot spots [21], [27], [64].

The specific but extremely complex effects we found for salt ions also on well-folded proteins imply that in addition to their central roles in mediating protein aggregation, salt ions may also act to modulate various biological functions of proteins.

They promote protein folding, prevent protein aggregation, foster protein degradation, disassemble protein complexes, and modulate protein protein interactions.