Sentence examples for modulate neuronal development from inspiring English sources

These structures elucidate the molecular determinants underlying polyproline ligand selection by the FE65 WW domain and provide a framework for the design of small molecules that would interfere with FE65 WW ligand interaction and modulate neuronal development and APP signaling.

Lines of evidence suggest that ECM proteins modulate neuronal development and plastic changes.

Synapsins also modulate neuronal development such as establishment of neuronal polarity, neurite elongation and synapse formation [ 14, 12- 18].

The second gene in common is the CAMK1D (calcium/calmodulin-dependent protein kinase ID) gene that encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases family of calmodulin kinases [ 55], which modulate neuronal development and plasticity [ 56].

Since TC007490/D2R RNAi beetles died during the larval stage, TC007490/D2R might be playing a critical role in the growth and development of larvae perhaps by modulating neuronal development and locomotor activity as reported in D. melanogaster.

These are the first aptamers to modulate neuronal growth.

The current review highlights similarities in the signaling cascades that modulate neuronal positioning during development, and synaptic plasticity in the adult, with a focus on reelin, a glycoprotein that is increasingly recognized for its dual role in the formation and maintenance of neural circuits.

While ionotropic NMDA-, andA-, and kainate-type glutamate receptors (iGluRs) mediate fast synaptic transmission, metabotropic glutamate receptors (mGluRs) (mGluR1 and mGluR5) modulate neuronal excitability and development, synaptic plasticity, transmitter release, and memory function via a variety of intracellular second messenger systems [ 11– 13].

In addition, NO may also act via nitrosylating other proteins, whereby it is able to modulate dendrite growth during neuronal development (Zhang et al. 2010).

Moreover, miRNAs play an important role in modulating gene expression during neuronal development, from early neurogenesis to synaptogenesis, as well as in maintenance of neuron function [20].

This morphological and functional plasticity is necessary for correct neuronal development and modulates numerous behavioural adaptations such as memory formation and addiction (Kandel, 2001; Calabresi et al, 2007).