Sentence examples for modulate neural stem from inspiring English sources

Moreover, fluoxetine has been found to modulate neural stem cell survival and serotoninergic differentiation through modulating Bcl-2 expression [ 46] as well as to protect neurons against microglial activation and subsequent release of multiple pro-inflammatory and cytotoxic factors [ 47].

We explore the concept of modulating neural stem cells and their niches for brain repair using nanotechnology-based approaches.

We showed here that the genes encoding for molecules that modulate adult neural stem cell proliferation and fate are transcribed in the CP.

Neogenin and RGMa may promote survival of NSPCs during embryogenesis, perhaps in modulating the number of neural stem and progenitor cells and may assume another role postnatally, perhaps primarily related to axonal pathfinding and guidance.

Here, JmjD3 is one of the early neural differentiation regulators modulated by BMP4 in neural stem cells and is crucial to activate TGFβ-responsive genes [ 204, 205].

Our studies further suggest that modulating the activity of Wnt/β-catenin signalling, through the expression of Fezf2, might provide a powerful means of modulating the differentiation fates of neural stem cells, reprogramming postmitotic neurons or inducing neuronal plasticity.

Neural stem cells can modulate the ischemic environment via the upregulation of survival-promoting/neurotrophic factors such as BDNF and/or by restoring neurotransmitter function by integrating in existing networks and improving network circuitry.

Oligodendrogenesis is modulated by molecular pathways that commit neural stem cells and glial progenitors to the oligodendrocyte lineage.

Here we show that polypyrrole (PPy), a commonly used conducting polymer, can be tailored to modulate survival and maintenance of rat fetal neural stem cells (NSCs).

Given that low oxygen tensions maintain undifferentiated states of embryonic, hematopoietic, mesenchymal, and neural stem cell phenotypes and modulate proliferation and cell-fate commitment [ 28], it is reasonable to assume that a much lower oxygen tension than that of ambient air in some specific environments of the cochlea may be more suitable for stem or progenitor cell populations to reside.

These results strongly suggest that APP-BP1 modulates the cell cycle progression of fetal neural stem cells and that APP antagonistically regulates the function of APP-BP1 in cell cycle progression from G1 to S Phase.