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Moreover, many of these signature genes are members of signaling pathways that modulate neural precursor cell proliferation and differentiation in the corresponding regions of the CNS [6], [113].
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In order to modulate the fate of transplanted cells, we advocate transplanting gene-modified neural precursor cells.
Moreover, NDRG1 upregulates neural precursor cell expressed developmentally downregulated 4-like (NEDD4L), which modulates the TGF- β pathway (Kovacevic et al, 2012).
The neural plate is composed of neural precursor cells, known as neuroepithelial cells, which develop into the neural tube (see below Morphological development).
neural precursor cells.
Human embryonic neural precursor cells.
That patent covers methods for turning mammalian ES cells into neural precursor cells.
Small discreet defects were detected early shortly after gastrulation with the alteration in CNS neural precursor cell fates in a number of identified neural precursors.
Geminin is preferentially expressed in neural precursor cells, and expression is down-regulated before neural differentiation [7] [6].
Sincere thanks to Dr. Jeanette Nardelli for her expert advice with neural precursor cell culture from the neural tube.
However, the assumption that CD133 is expressed constitutively in neural precursor cells has not been examined.
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