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In line with this, BNIP3 has been shown to modulate mitochondrial mass and mitochondrial fitness in cardiac myocytes, fibroblasts and in the liver.
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Future studies addressing NT-PGC-1α's regulatory role in modulating mitochondrial mass within the context of neuronal differentiation and survival using our cellular paradigm are relevant based on the recent evidence of NT-PGC-1α enhancing mitochondrial biogenesis in brown adipocytes (Zhang et al., 2009).
In line with intramitochondrial proteolytic stress modulating mitochondrial dynamics, the expression of dOTC within control siRNA-treated cells led to a significant reduction of mitochondrial mass.
Intense training makes a difference, he said, because it can make double the mitochondrial mass.
Figure 14 AgNPs modulate mitochondrial transmembrane potential.
Their mitochondrial mass was comparable.
Mitochondrial mass was quantified by measuring citrate synthase activity.
An alternative strategy, whose feasibility is supported by increasing experimental evidence, is to modulate mitochondrial ROS production itself.
Mitochondrial mass -- and athletic performance -- is further increased by high-intensity, burst-type training.
Mitochondrial biogenesis involves mitochondrial DNA (mtDNA) replication and mitochondrial mass increase.
In their turn, superoxide flashes modulate mitochondrial function, as they cause mitochondrial depolarizations.
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