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In their turn, superoxide flashes modulate mitochondrial function, as they cause mitochondrial depolarizations.
Growth factor-mediated pathways have been reported to modulate mitochondrial function and regulate the activity of the pro-apoptotic protein, BAD [15].
EGFR and Src can translocate to mitochondria by binding the subunit
Through intranuclear translocation, the RTG proteins induce the transcription of specific target genes, which in turn modulate mitochondrial function.
At subcellular level, NO was shown to modulate mitochondrial function through reversible and irreversible interactions with respiratory chain complexes.
Pharmacologic approaches to modulate mitochondrial function have, to date, been limited and have recently been reviewed [ 2, 3].
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Proline can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress.
Objectives Determine if exposure to septic serum modulates mitochondrial function in a live naïve kidney slice.
H2O2 has a major role in modulating mitochondrial function by inhibiting activities of the mitochondrial enzyme in a fully reversible fashion [3, 4].
However, during the last decade, the transcription-independent activity of the p53 protein has emerged as an important mechanism by which p53 modulates mitochondrial function.
Multiple kinases and phosphatases in mammals are identified to translocate to mitochondria and play critical roles in modulating mitochondrial function [64].
More suggestions(16)
modulate synaptic function
modulate mitochondrial membrane
modulate mitochondrial energy
modulate immune function
modulate mitochondrial perturbation
modulate leukocyte function
modulate inhibitory function
modulate mitochondrial activity
modulate vascular function
modulate endothelial function
modulate macrophage function
modulate mitochondrial respiration
modulate mitochondrial physiology
modulate neural function
modulate mitochondrial biogenesis
modulate biological function
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