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Regarding OPA1 cleavage, a series of proteases localized to mitochondria including the ATPase family gene 3-like 2 (and3l2) and high temperature requirement protein A2 (Htrare areportedtod to participate in and modulate mitochondria morphology and functional activity.
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Mitochondria dynamics regulate processes associated with mitochondria morphology such as mitochondria biogenesis, localization, and distribution as well as the morphology itself [2].
c Graphs present data from the analysis of mitochondria morphology using ImageJ software.
The mitochondria apoptosis pathway is signified by the release of cytochrome c, a change in the mitochondria morphology and permeability.
We have shown that interference with CTMP expression and/or protein maturation critically affected mitochondria morphology.
Overexpression of LETM1 in A549 cells caused fragmented pattern of mitochondria morphology demonstrated by CLSM (Fig. 5A).
In addition, previously published cases were examined for mitochondria morphology.
Quantitative analysis of mitochondria morphology was performed as described.
Mef2>Ret MEN2B overexpression in control flies did not alter normal mitochondria morphology (Fig 2C, G, L, M).
Mitochondria morphology was visualized by transfecting RPE cells with plasmid expressing RFP-ANT1.
Complex V seems to play an important role in mitochondria morphology [ 5].
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