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Even if the gene is mechanistically linked to prostate tumorigenesis, it can be detected by GWAS only if it carries genetic variants that modulate its function.
Because the pKa of Glu142 is near the pH of its native marine environment, changes in pH may act to modulate its function in the cell.
Thus, we considered that CHEB42A might associate with LLZ and modulate its function.
Thus, Eps8 represents an actin remodeler that can be dynamically regulated to modulate its function.
Consistent with this, a shift in Rad52 protein mobility was observed at 12 and 24 hours likely reflecting phosphorylation that might modulate its function in HR.
It is worth noting that we cannot, of course, rule out the possibility that pathological changes in APP Thr668 phosphorylation state might modulate its function or metabolism.
Similar(42)
Plant evolutionary history influences the taxonomic composition of the root-associated bacterial community, but whether it can also modulate its functioning is unknown.
Because of the large size of the hot-spot interface of NUPR1, small molecules could not be adequate to modulate its functions.
RAPTOR (regulatory associated protein of mTOR) and RICTOR (rapamycin-insensitive companion of mTOR) are key partnering proteins which complex with mTOR and modulate its functions.
The multiple functions of the unique retrograde motor myosin VI appear to be regulated in a number of ways; for example by the presence or absence of inserts in both the tail and motor domains, by PIP2/liposome binding, by phosphorylation, by calcium binding, by binding partners and possibly by other signals and modifications, which may together modulate its functions in the cell.
It has been reported that WFS1 binds to SERCA and modulates its function [ 41].
More suggestions(15)
modulate its functional
influence its function
modulate its virulence
modulate its host
modulate its acidity
modulate its index
modulate its aggregation
modulate its surface
modulate its expression
modulate its capacity
modulate its amplitude
modulate its manifestation
modulate its degradation
modulate its structure
modulate its role
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