Sentence examples for modulate its expression from inspiring English sources

In this context, we synthesized a DNA vector that encodes an active form of miR-155 in order to modulate its expression in DCs and study how it influences their ability to prime naïve antigen-specific T cells.

Spatial localization of a gene within the nucleus can modulate its expression, leading either to its activation or repression [1].

Continued efforts to modulate its expression and/or activity will likely allow for novel anabolic agents for conditions of bone loss.

The fact that blocking the Hh receptor smoothened by the specific inhibitor cyclopamine was not able to mimic the effect of forskolin, and, in the case of RAR-β, even modulate its expression in the opposite direction, indicates that Hh signaling is not participating on the regulation of RAR-β and RXR-γ expression by cAMP.

There results suggest that miR-34a can directly target HNF4G and modulate its expression.

Similarly, the ability to pharmacologically modulate its expression will undoubtedly kick-start efforts on this track.

In this study, we evaluated the critical role of CXCL-8 in melanoma growth and progression by modulating its expression in melanoma cell lines expressing different levels of CXCL-8.

HIF-1β was constitutively expressed in the cells, and none of those stimuli modulated its expression.

These mechanisms alter the way the transcriptional factors bind the DNA, modulating its expression.

As this enzyme has an important role in processing antigenic peptides for the HLA I molecules, a variant that drastically modulates its expression levels might affect risk of autoimmunity.

This latter hypothesis is strengthened by the fact that the transporter SCL16A3, necessary for pre-implantation [40] was up-regulated in response to C. burnetii stimulation, whereas TNF stimulation down-modulated its expression.