Sentence examples for modulate insulin sensitivity from inspiring English sources

When a preventive strategy is not feasible or has not been correctly pursued, the use of the insulin-sensitizing agent metformin has been proposed to modulate insulin sensitivity during pregnancy in women with PCOS.

In this study, we investigate whether pharmacologic agents that modulate insulin sensitivity or normalize insulin levels will diminish the proliferative response to estrogen.

PPARγ regulates the expression of many genes although the exact PPARγ target genes that modulate insulin sensitivity are as yet unidentified.

Targeting and synthesizing selective inhibitors of this molecule have been shown to modulate insulin sensitivity [126].This gene eventually has been reported to interact with β-catenin [78].

PPARγ has pleiotropic functions affecting a wide range of fundamental biological processes including the regulation of genes that modulate insulin sensitivity, adipocyte differentiation, inflammation and atherosclerosis.

Sustained Gcg-XTEN levels may therefore impact a variety of signaling pathways that modulate insulin sensitivity (among other factors) leading to the observed effects.

Furthermore, there are also studies in humans suggesting that the fatty acid composition of phospholipids in the sarcolemma modulates insulin sensitivity (Storlien et al. 1991; Borkman et al. 1993).

Besides its role in regulating adiposity, Fsp27 also plays an important role in modulating insulin sensitivity.

Further studies are needed to clarify whether IL-18 modulates insulin sensitivity in human adipose tissue.

Thus, GH seems to play an important role in modulating insulin sensitivity and longevity.

Further, AMPKα2 knockout mice show whole body insulin resistance, suggesting that AMPK may play a role in modulating insulin sensitivity.