Sentence examples for modulate insulin activity from inspiring English sources

So they decided to fight hormone with hormone and to test the effects of adiponectin, a hormone made in fat cells that seems to modulate insulin activity in two different ways.

We showed recently that Glis3 is a potent transactivator of the insulin promoter (Yang et al, 2009); it physically and functionally interacts with PDX1, MAFA and NEUROD1 to modulate insulin promoter activity (Yang et al, 2009).

Also glucocorticoids modulate insulin and Egfr activity in rats, depending on the animals' dietary state [ 70].

Although a novel inference, it seems possible that adiponectin is secreted to modulate insulin sensitivity when activity levels are insufficient to do so.

Hopefully, the identification of other novel natural products that significantly modulate insulin and/or pdx1 promoter activity will point to new methods of controlling beta-cell function and fate and eventually to new diabetes therapeutics based on the lead structures of these natural products.

These results suggest that ATM-dependent stress pathways mediate susceptibility to the metabolic syndrome and that chloroquine or related agents promoting ATM activity could modulate insulin resistance and decrease vascular disease.

Thus, the activity state of the mTOR pathway can modulate insulin sensitivity in humans and mTOR inhibitors prevent nutrient-induced insulin resistance [ 70].

Doyle, M. E. & Egan, J. M. Pharmacological agents that directly modulate insulin secretion.

Sen, S., Talukdar, I. & Webster, N. J. SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing.

Leptin has been shown to be able to modulate insulin secretion.

The macrophages release inflammatory molecules that are thought to impair insulin activity.