Sentence examples for modulate host GTPases from inspiring English sources

Small GTPases are important modulators of actin dynamics and downstream signaling and many bacteria evolved ways to modulate host GTPases.

Thus, different receptors (for opsonized or nonopsonized parasites) trigger different GTPases that modulate host cell responses to Leishmania.

In both proteins we identified a WxxxE motif, previously shown to be an essential structural component in a family of bacterial type III secretion system effectors that modulate host actin dynamics by functioning as guanine nucleotide exchange factors of host GTPases.

In summary, we demonstrate that microbiota modulate host miRNA expression.

Some of the yet unidentified molecules may interfere with host cell signaling pathways and thereby modulate host cell behavior [38].

Intracellular pathogens modulate host cell function to promote their survival.

Few other viruses also target CLU to modulate host responses.

Because the rapid turnover of GTPase signaling networks is essential for receptor localization and cytokine secretion, microbial regulation of host GTPases and their downstream interactions may be a powerful mechanism of immune evasion.

Several virulence factors are known to affect host GTPase by causing post-translational modifications on GTPases.

Microbes during coevolution with host have found that affecting the host GTPase is one of the best ways to hijack host cellular machinery critical for pathogenesis.

The effector DrrA, for example, mediates the recruitment and activation of the host GTPase Rab1 to the vacuole containing Legionella.