Sentence examples for modulate gene activity from inspiring English sources

In microbial systems, transcription factors bind directly to gene promoters and modulate gene activity via direct repression or activation.

Epigenetic alterations are able to modulate gene activity without affecting their nucleotide sequence.

One hint comes from evidence that these amino acids disrupt interactions between chromatin and 'effector' proteins, which modulate gene activity.

They can be considered as a way to modulate gene activity, alternative or complementary way to gene mutations.

It is intriguing to postulate that many ncRNAs might finely modulate gene activity by acting as regulatory elements.

Like their targeted effects, the global activity of the histone-modifying enzymes can modulate gene activity (Vogelauer et al, 2000).

ompR and envZ belong to the two-component signalling family and modulate gene activities of ompF and ompC, the two major OMP genes that code for the tri-barrel porin [7].

Gene therapy is an extension of drug and surgical treatments, and part of a continuum of medical interventions that introduce or modify DNA or modulate genes' activity.

Increasing evidences verify that 20 24 nucleotide-long miRNAs play important roles in growth, development, and stress adaptations in planta via modulating gene activity [ 1, 2].

Epigenetic processes, such as DNA methylation, histone modifications, generation of small RNAs (sRNA), and transposable element activity, play essential roles in modulating gene activity in response to environmental stimuli.

To determine if the regions contacted predominantly by the Kcnq1 promoter are regulatory elements, we integrated comparative genomics data and publicly available genome-wide chromatin immunoprecipitation (ChIP) profiles and identified DNA sequences that are candidates for modulating gene activity.