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The PI3K/Akt pathway can modulate functions of ABC transporters through various mechanisms.
Antisera elicited by MCPs recognize native gp120 but not denatured gp120, and modulate functions of the native protein.
Also, it can bind and modulate functions of cytoskeleton by binding to proteins like talin and paxillin.
Changes in intracellular lipid homeostasis also modulate functions of macrophages as important members of the innate immunity.
These examples showed that some AS events can modulate functions of proteins especially for ones with multiple domains.
We tested the hypothesis that toxin-like proteins exist in viruses and that they act to modulate functions of their hosts.
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To investigate whether blockade of EPHA2 or EPHB4 using siRNA under hyperoxia can modulate function of human airway epithelial cell line (BEAS-2B).
Tailoring three-dimensional (3D) biomaterial environments to provide specific cues in order to modulate function of encapsulated cells could potentially eliminate the need for addition of exogenous cues in cartilage tissue engineering.
To evaluate immune modulate function of Tl-GAL in host inflammatory response, we constructed recombinant Tl-GAL (rTl-GAL) using an Escherichia coli expression vector system and treated to intestinal inflammation mice.
ID3 is one of the ID proteins that modulate function of E2A proteins [23].
In addition, activated complement factors modulate function of adaptive immunity 12.
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