Sentence examples for modulate endothelial activation from inspiring English sources

Fish oil has been shown to modulate endothelial activation possibly by reducing ROS and therefore leading to the subsequent inactivation of the NF-κB system of gene transcription.

In vitro mRNA profiling suggests that FOXO1 mediates high-glucose induced mRNA expression of genes that modulate endothelial cell activation such as CCL2 and CCL5, enhances apoptosis by increasing mRNA levels of BCL2 and CASP3, and increases the basal expression of genes that affect angiogenesis such as ITGA5 and ITGAV-M [ 29].

At this regard, some findings suggest that both major and minor olive oil components may modulate inflammation and endothelial activation.

In this study, we show that different VEGF-A isoforms have differing capabilities to modulate endothelial cell migration by regulating the activation and nuclear localisation of a key transcription factor (Fig. 7).

Thus, the expression patterns of extracellular miRNAs that modulate endothelial function and inflammatory signaling may provide key insights into mechanisms that contribute to endothelial activation and injury in the setting of severe sepsis.

Ischaemia leads to endothelial activation with increased expression of endothelial adhesion molecules [5].

Pathological factors modulate endothelial targeting and uptake of nanocarriers.

Widespread endothelial activation and dysfunction often precede clinical sepsis.

Targeting endothelial adhesion molecules may provide a more specific way to image inflammation through the detection of endothelial activation.

In experimental animal models of AKI, endothelial activation and damage lead to both disruption of renal endothelial cell integrity and endothelial matrix breakdown [3, 22].

Toxins can also modulate the immune response by influencing endothelial biology, and can modulate endothelial function by influencing the response of leukocytes.