Sentence examples for modulate drug loading from inspiring English sources

A variety of polymers have been used in conjunction with sodium alginate to modulate drug loading and modify drug release kinetics (Pillay and Fassihi 1999; Nochos et al. 2008; Hua et al. 2010).

While polymeric micelles can be developed with improved drug loading capabilities by modulating hydrophobicity and hydrophilicity of the micelle forming block co-polymers, they can also be successfully cancer targeted by surface modifying with tumor-homing ligands.

However, the percent drug loading can be modulated by varying the hydrophilic-to-hydrophobic block ratio (Kim and Lee 2001).

Their composition can be adjusted to modulate drug release and they can encapsulate both hydrophilic and lipophilic compounds with high drug loading (Loira-Pastoriza et al. 2014).

Initially, sodium alginate and calcium chloride concentrations were methodically modulated when beads were prepared, as these parameters were reported to enhance drug loading and impart controlled-release characteristics (Al-Musa et al. 1999; Blandino et al. 1999).

Although data for more drugs are needed, drug loading of nanocarriers is a formulation factor that can be modulated to control permeation of nanoencapsulated drugs with different molecular characteristics through microporated skin for different skin delivery purposes.

The 3D printed compartmentalized shells were loaded with filaments containing active pharmaceutical ingredient (API) and selectively sealed to modulate drug dissolution.

Compared to solid dispersions of the same drug and polymer, scCO2-impregnated microcontainers exhibit a more reproducible drug loading and a faster dissolution rate of the active compound which allows drug release to be modulated.

Hydrophobic drug loading and structural stability of drug after drug loading are the major challenges in the drug delivery.

Therefore, the introduction of thermosensitive polymers on polymeric nanoparticles might be a potential approaches to modulate drug release behaviors.

Eberl, M. et al. Tumor architecture and notch signaling modulate drug response in basal cell carcinoma.