Sentence examples for modulate dna function from inspiring English sources

Methylation of DNA is accompanied by histone post-translational modifications that modulate DNA function, regulating chromatin structure and determining the transcriptional state of the DNA wrapped around it.

Further studies are needed to elucidate the specific role of the rare variants in modulating DNA binding and DNA repair function, as protein recruitment to focal laser damage represents only a limited part of the DNA repair functions of XPC.

Another mechanism by which the DNA binding activity of the H19 DBD could be modulated is that histidine, with a pI of 7.6, could conceivably function as a pH sensor such that small changes in nuclear pH could modulate DNA binding.

Such a model would not be consistent with the sole DNA repair function of mouse SIRT6 being to modulate DNA-PKcs activity, as DNA-PKcs knockout animals do not display a dramatic metabolic phenotype [ 1].

Fanzio, P. et al. Modulating DNA translocation by a controlled deformation of a PDMS nanochannel device.

We examined how arsenic modulates DNA damage by other chemicals.

ACF may modulate the function of the DNA binding proteins throughout different stages of the parasite life cycle.

Here we questioned whether hRad18 can also regulate FANCD2 monoubiquitination upon DNA damage, becasue HHR6 cooperates with hRAD18 to modulate the function of proteins involved in DNA damage responses [19] [21].

We suggest that low-complexity lysine-rich sequences have evolved repeatedly to modulate the function of unrelated DNA-binding proteins.

We propose that lysine-rich LCRs have evolved repeatedly to modulate the function of unrelated DNA-binding proteins, in the case of M. smegmatis Ku and Hlp to respond more efficiently to environmental stresses with the potential to damage genomic DNA.

Our data also suggest that the chromatin structure of DNA is able to modulate the function of transcription factors in a dramatic manner.