Sentence examples for modulate cleavage of from inspiring English sources

In contrast, iGSMs are still able to modulate cleavage of most mutant substrates.

Glycans located near antigenic peptide epitopes interfere with antibody recognition [28], and glycans near the proteolytic activation site of HA modulate cleavage and influence infectivity of the influenza virus [29].

Another option is to use a genetic approach to modulate cleavage such as induction of exon 12 skipping in huntingtin pre-mRNA using oligonucleotides.

Challand et al. observed the addition of glyoxylate to assays limits Cα Cβ tyrosine bond cleavage, suggesting dehydroglycine might modulate uncoupled cleavage of SAM as a mechanism ensuring dehydroglycine production and incorporation into the thiazole carboxylate is a coordinated event between ThiH and ThiG.

Even in primates experiencing lower levels of postcopulatory selection and lower semen coagulum thickness like gorilla (Dorus et al. 2004), it seems that the role of EPPIN in modulating the cleavage of SEMG1 is not affected.

Another striking feature that might modulate α-cleavage of PrPC is the strong hydrophobicity of the residues neighbouring the cleavage site.

These data suggest that N3-2A/MoBA interferes predominantly with processing of APP by β-secretase and does not modulate γ-cleavage of β-CTF (Fig 2J).

Recently, their family members were shown to regulate neurite outgrowth, morphology and functions [ 18], late steps of spermatogenesis [ 19] and modulate the first cleavage of mouse preimplantation embryos [ 20].

This indicates that the level of bisecting GlcNAc on BACE1 is elevated with disease progression in the human brain, suggesting that this abnormal change in BACE1 glycosylation is involved in AD pathogenesis by modulating β-site cleavage of APP.

Essentially no C1 was observed when the C40 construct was transfected into Hpl cells (Fig. 4B C), thereby establishing that the region encompassing residues 100 129 is essential for modulating α-cleavage of PrPC.

Our study offers the possibility of modulating the cleavage rates of LexA across a large range to assess the impact on bacterial mutation and survival directly under varying degrees of stress.