Sentence examples for modulate chromatin accessibility from inspiring English sources

Chromatin architectural proteins interact with nucleosomes to modulate chromatin accessibility and higher-order chromatin structure.

The DCSR pairs represent the locations of imbalances of chromatin accessibility between alleles and are ideal to reveal chromatin motifs that may directly modulate chromatin accessibility.

(9, 55, 56, 59– 61) Pioneer factors have the capacity to associate with condensed chromatin independently of other factors and can directly modulate chromatin accessibility.

In the same analogy, we proposed that a chromatin motif that can be recognized by a TF may modulate chromatin accessibility.

The DCSR pairs represent the locations of imbalances of chromatin accessibility between alleles and are ideal to identify motifs that may directly modulate chromatin accessibility [ 11].

The forkhead protein FOXA1 is a critical interacting partner of the AR, functioning as a pioneer factor to modulate chromatin accessibility and facilitate transcription (Jozwik & Carroll, 2012).

Epigenetic variation – polymorphisms at the level of DNA methylation or histone modifications – modulates chromatin accessibility, which can perturb transcriptional activity and spur phenotypic variation.

This is a crucial step in modulating chromatin accessibility at NF-κB responsive promoter [ 19, 20].

HDACs play major roles in modulating chromatin accessibility during transcription, replication, recombination, and repair [ 61, 62]; however, the role of individual HDACs in these processes is still unclear.

Using nano-LC-MS/MS, a set of histone modifications was detected in HIV- versus mock-infected cells, providing insight on how the virus modulates chromatin accessibility to assure its transcription during infection [ 99].

Besides regulating chromatin accessibility, some lncRNAs can also directly regulate specific transcription factors to modulate gene expression during myogenesis.