Sentence examples for modulate chondrocyte responses from inspiring English sources

Through interactions with α5β1 integrin and thrombospondin, CD47/IAP may modulate chondrocyte responses to mechanical signals.

The purpose of this study was to determine the ability of hyaluronan in the pericellular matrix to modulate the chondrocyte responses to BMP-7 or TGF-β1.

Osmotic loading is known to modulate chondrocyte (cell) height, width and volume in articular cartilage.

Some studies suggest that statins modulate chondrocyte metabolism by reducing prenylation of key signaling molecules that control expression of collagen-degrading enzymes [25].

Oxygen is a critical parameter proposed to modulate chondrocyte metabolic activity [ 3].

Crosstalk between the canonical and non-canonical pathways can modulate chondrocyte differentiation and cartilage matrix synthesis.

Chondrocyte responses towards mechanical stimulation have been less studied.

Chondrocyte responses to monocyte/macrophage signals are well described.

Other members of the IL-6 family that act through receptors that heterodimerize with gp130 may also modulate chondrocyte function.

Although leptin may be a local factor able to modulate chondrocyte functions, its contribution in OA remains unclear.

This suggests that mechanical stimuli may be useful in modulating chondrocyte metabolism in tissue engineering systems using fibrillar protein scaffolds.