Sentence examples for modulate cellular responses from inspiring English sources

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Methylated Reptin binds to the promoters of a subset of hypoxia-responsive genes and negatively regulates transcription of these genes to modulate cellular responses to hypoxia.

Previous studies reported that surface topography and substrate rigidity provide biomechanical cues to modulate cellular responses such as alignment, migration and differentiation.

Rapid degradation of ATP to ADP may alternatively modulate cellular responses.

The induction of intraperitoneal abscesses by other zwitterionic polysaccharides is based on their ability to directly activate T-cells, which in turn modulate cellular responses at the infection site [14], [28].

These findings suggest the presence of significant differences between EPOR-mediated signaling in hematopoietic cells compared to tumor cells and that the level of EPOR expression in tumor cells may modulate cellular responses to exogenous EPO.

We suggest that MAP4K3 has two independent functions during wing development, one related to the activation of the JNK pathway in response to stress and other in the assembling or activation of the TORC1 complex, being critical to modulate cellular responses to changes in nutrient availability.

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Meinert, C. et al. Tailoring hydrogel surface properties to modulate cellular response to shear loading.

Four major approaches are currently being explored in preclinical models, some also in patients: combination with agents that modulate cellular response and disposition of oxazaphosphorines; antisense oligonucleotides directed against specific target genes; introduction of an activating gene (CYP3A4) into tumor tissue; and modification of dosing regimens.

It is concluded that, in addition to direct inactivation of reactive cytotoxic CENU species, GSH may also modulate cellular response to CENUs by quenching chloroethylated DNA, thereby decreasing the formation of potentially lethal DNA cross-links.

BRCA1 expression can modulate cellular response to chemotherapy.

Polyamines interact with signaling pathways to modulate cellular response.

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